An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization

Michel Jourdan, Anouk Caraux, John De Vos, +7

Blood

JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen‐activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells

John De Vos, Michel Jourdan, Karin Tarte, +2

British Journal of Haematology

Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays

John De Vos, Thomas Thykjær, Karin Tarte, +10

Oncogene

Oligonucleotide ArraysMedicineCancer GenomicsCell BiologyGene Expression +7

The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor

Anne Catherine Sprynski, Dirk Hose, L. Caillot, +15

Blood

Identifying intercellular signaling genes expressed in malignant plasma cells by using complementary DNA arrays

John De Vos, Guilhem Couderc, Karin Tarte, +6

Blood

A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cells

Michel Jourdan, Jean‐Luc Veyrune, John De Vos, +3

Oncogene

InflammationHuman Myeloma CellsCytokineMedicineImmunology +6

Characterization of a Transitional Preplasmablast Population in the Process of Human B Cell to Plasma Cell Differentiation

Michel Jourdan, Anouk Caraux, Gersende Caron, +14

The Journal of Immunology

Lymphocyte DevelopmentImmunologyImmunologic MechanismCell ProliferationCell Differentiation +14

GenomicScape: An Easy-to-Use Web Tool for Gene Expression Data Analysis. Application to Investigate the Molecular Events in the Differentiation of B Cells into Plasma Cells

Alboukadel Kassambara, Thierry Rème, Michel Jourdan, +4

PLoS Computational Biology

EngineeringGeneticsDna MicroarraysGenomicsPlasma Cells +19

Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma

Karène Mahtouk, Dirk Hose, P Raynaud, +12

Blood

The myeloma cell antigen syndecan‐1 is lost by apoptotic myeloma cells

Michel Jourdan, Martine Ferlin, Éric Legouffe, +6

British Journal of Haematology