Concepedia

Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A inhibitor

Arimappamagan Arivazhagan, Durairaj Mohan Kumar, Vinay Sagar, Irene Rosita Pia Patric, Sambandam Sridevi, Balaram Thota, Mallavarapu R. Srividya, Krishnarao Venkatesh Prasanna, Kandavel Thennarasu, Neelima Mondal,

Journal of Neuro-Oncology · 2011 · 29 citations · 26 references

DOI

Concepts

References

26

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

Roger Stupp, Monika E. Hegi, Warren Mason et al. · The Lancet Oncology · 2009 · 7.8K citations

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Amplification and Deletion of Topoisomerase IIα Associate with ErbB-2 Amplification and Affect Sensitivity to Topoisomerase II Inhibitor Doxorubicin in Breast Cancer

Tero A.H. Järvinen, Minna Tanner, Virpi Rantanen et al. · American Journal Of Pathology · 2000 · 385 citations · Full text

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DNA Topoisomerase IIβ and Neural Development

Xia Yang, Wei Li, Elizabeth D. Prescott et al. · Science · 2000 · 345 citations

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Bevacizumab Plus Irinotecan in Recurrent WHO Grade 3 Malignant Gliomas

Annick Desjardins, David A. Reardon, James E. Herndon et al. · Clinical Cancer Research · 2008 · 171 citations · Full text

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Isolation of genetic suppressor elements, inducing resistance to topoisomerase II-interactive cytotoxic drugs, from human topoisomerase II cDNA.

Andrei V. Gudkov, C R Zelnick, Alexander R. Kazarov et al. · Proceedings of the National Academy of Sciences · 1993 · 136 citations · Full text

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