Lab on a Chip · 2015 · 48 citations · 10 references
EngineeringComputer EngineeringComputer ScienceComputer ArchitectureLow-power DesignDevice ScalingDigital Integrated Circuit DesignDigital Logic DesignLogic SynthesisLow-power Digital Circuit DesignPneumatic SystemsDensityDigital Logic CircuitsHigh-speed Logic DesignLogic DevicesLogic Element ArchitectureLogic OptimizationPneumatic Circuit Design
The scaling of integrated circuits to smaller dimensions is critical for achieving increased system complexity and speed. Digital logic circuits composed of pneumatic microfluidic components have to this point been limited to a circuit density of 2-4 gates cm(-2), constraining the complexity of the digital systems that can be achieved. We explored the use of precision machining techniques to reduce the size of pneumatic valves and resistors, and to achieve more accurate and efficient placement of ports and vias. In this way, we attained an order of magnitude increase in circuit density, reaching as high as 36 gates cm(-2). A 12-bit binary counter circuit composed of 96 gates was realized in an area of 360 mm(2). The reduction in size also brought an order of magnitude increase in speed. The frequency of a 13-stage ring oscillator increased from 2.6 Hz to 22.1 Hz, and the maximum clock frequency of a binary counter increased from 1/3 Hz to 6 Hz.
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Static control logic for microfluidic devices using pressure-gain valves
James Weaver, Jessica Melin, D. Stark et al. · Nature Physics · 2010 · 138 citations
Engineering, Biomedical Engineering, Mechanical Engineering +16