Cecal Ligation and Incision: An Acute Onset Model of Severe Sepsis in Rats

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*

Anand Kumar, Daniel Roberts, Kenneth E. Wood et al. · Critical Care Medicine · 2006 · 6.1K citations

Veterinary Medicine, Infectious Diseases, Antimicrobial Pharmacotherapy +13

Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis

Fernando A. Bozza, Jorge I. Salluh, André Miguel Japiassú et al. · Critical Care · 2007 · 741 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +13

COMPARISON OF THE MORTALITY AND INFLAMMATORY RESPONSE OF TWO MODELS OF SEPSIS: LIPOPOLYSACCHARIDE VS. CECAL LIGATION AND PUNCTURE

Daniel G. Remick, David E. Newcomb, G. Bolgos et al. · Shock · 2000 · 526 citations

Veterinary Medicine, Immunology, Pathology +14

The enigma of sepsis

Niels C. Riedemann, Renfeng Guo, Peter A. Ward · Journal of Clinical Investigation · 2003 · 509 citations · Full text

Veterinary Medicine, Pharmacotherapy, Translational Sciences +11

Chemotaxis Inhibitory Protein of <i>Staphylococcus aureus</i>, a Bacterial Antiinflammatory Agent

Carla J. C. de Haas, Karin Ellen Veldkamp, Andreas Peschel et al. · The Journal of Experimental Medicine · 2004 · 466 citations · Full text

Life Sciences, Immunology, Microbiology +17