Polymeric nanomedicine for cancer therapy

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations

Pharmacy, Cell Biology, Immunology +11

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Medicine, Oncology, Pharmacology +12

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance

L. R. Hirsch, R. Jason Stafford, James A. Bankson et al. · Proceedings of the National Academy of Sciences · 2003 · 3.9K citations · Full text

Engineering, Biomedical Engineering, Oncology +17

Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment

Susan K. Hobbs, Wayne L. Monsky, Fan Yuan et al. · Proceedings of the National Academy of Sciences · 1998 · 2.4K citations

Medicine, Cancer Biology, Oncology +17