Improvement of an in vitro stem cell assay for developmental toxicity: the use of molecular endpoints in the embryonic stem cell test

The <i>in vitro</i> development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

Thomas Doetschman, Harald Eistetter, Margot Katz et al. · Development · 1985 · 2K citations

Vitro Developmental Potential, Basal Lamina, Cell Culture +20

Retinoic Acid Embryopathy

Edward J. Lammer, Diane T. Chen, Richard M. Hoar et al. · New England Journal of Medicine · 1985 · 1.9K citations

Major Malformations, Developmental Biology, Retina +14

The ECVAM International Validation Study on <i>In Vitro</i> Embryotoxicity Tests: Results of the Definitive Phase and Evaluation of Prediction Models

Elke Genschow, Horst Spielmann, Gabriele Scholz et al. · Alternatives to Laboratory Animals · 2002 · 380 citations

In vitro differentiation of embryonic stem cells into mineralized osteoblasts

Nicole I. zur Nieden, G. Kempka, H J Ahr · Differentiation · 2003 · 349 citations

Tissue Engineering, Embryo Culture, Developmental Biology +10

Validation of the Embryonic Stem Cell Test in the International ECVAM Validation Study on Three <i>In Vitro</i> Embryotoxicity Tests

Elke Genschow, Horst Spielmann, Gabriele Scholz et al. · Alternatives to Laboratory Animals · 2004 · 340 citations

Embryotoxic Potentials, Toxicology Testing, Biomedical Engineering +19