Tacrolimus metabolite cross-reactivity in different tacrolimus assays

Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A

Robert E. Handschumacher, Matthew W. Harding, Jeffrey S. Rice et al. · Science · 1984 · 1.7K citations

Life Sciences, Biochemistry, Immunology +12

A receptor for the immuno-suppressant FK506 is a cis–trans peptidyl-prolyl isomerase

Matthew W. Harding, David Uehling, Stuart L. Schreiber · Nature · 1989 · 1.4K citations

Medicine, Immunology, Pharmacology +8

Pharmacokinetics of tacrolimus in liver transplant patients*

William J. Jusko, Wojciech Piekoszewski, Göran B. Klintmalm et al. · Clinical Pharmacology & Therapeutics · 1995 · 242 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Calcineurin Is a Key Signaling Enzyme in T Lymphocyte Activation and the Target of the Immunosuppressive Drugs Cyclosporin A and FK506^a

Neil A. Clipstone, Gerald R. Crabtree · Annals of the New York Academy of Sciences · 1993 · 128 citations

Life Sciences, Immunology, Pharmacology +14

Effect of hepatic dysfunction and T tube clamping on FK 506 pharmacokinetics and trough concentrations.

Ashokkumar Jain, Raman Venkataramanan, Evan M. Cadoff et al. · PubMed · 1990 · 98 citations

Pharmacy, Pharmacokinetics, Pharmacology +15