Effects of grapefruit juice and smoking on verapamil concentrations in steady state

Nonparametric Statistical Methods

Technometrics · 1999 · 6.2K citations

Natural Sciences, Biostatistics, Spatial Data Analysis +14

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.

Kenneth S. Lown, David G. Bailey, Robert J. Fontana et al. · Journal of Clinical Investigation · 1997 · 628 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +11

Disposition of intravenous and oral cyclosporine after administration with grapefruit juice*

Murray P. Ducharme, L H Warbasse, David J. Edwards · Clinical Pharmacology & Therapeutics · 1995 · 351 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +15

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents: Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins

Paul F. Hollenberg, David Edwards, Kan He et al. · UNC Libraries · 2019 · 311 citations · Full text

Agriculture, Pharmacokinetics, Pharmacology +9

The fate of naringin in humans: A key to grapefruit juice-drug interactions?

Uwe Fuhr, Anja L. Kummert · Clinical Pharmacology & Therapeutics · 1995 · 251 citations

Pharmacy, Pharmacokinetics, Pharmacology +12