Glucocorticoid-induced TNFR-related protein (GITR) ligand modulates cytokine release and NK cell reactivity in chronic lymphocytic leukemia (CLL)

Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

Veronika Groh, Jennifer D. Wu, Cassian Yee et al. · Nature · 2002 · 1.6K citations

Cancer Immunosurveillance, Immunology, T-cell Activation +9

Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine

Marc Beyer, Matthias Kochanek, Kamruz Darabi et al. · Blood · 2005 · 485 citations

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells

Kuibeom Ko, Sayuri Yamazaki, Kyoko Nakamura et al. · The Journal of Experimental Medicine · 2012 · 463 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +24

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3 <b>+</b> CD25 <b>+</b> CD4 <b>+</b> regulatory T cells

Kuibeom Ko, Sayuri Yamazaki, Kyoko Nakamura et al. · The Journal of Experimental Medicine · 2005 · 461 citations · Full text

Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells

Megan K. Levings, Romina Sangregorio, Claudia Sartirana et al. · The Journal of Experimental Medicine · 2002 · 426 citations · Full text

Lymphocyte Development, T-regulatory Cell, Immunology +21