Leptin Differentially Regulates NPY and POMC Neurons Projecting to the Lateral Hypothalamic Area

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene

Jeffrey L. Halaas, K.S. Gajiwala, Margherita Maffei et al. · Science · 1995 · 4.5K citations

Medicine, Endocrinology, Nutritional Sciences +17

Effects of the <i>obese</i> Gene Product on Body Weight Regulation in <i>ob</i> / <i>ob</i> Mice

Mary Ann Pelleymounter, Mary Jane Cullen, Mary Baker et al. · Science · 1995 · 4K citations

Life Sciences, Biochemistry, Endocrinology +17

The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity

Luı́s de Lecea, Thomas S. Kilduff, Christelle Peyron et al. · Proceedings of the National Academy of Sciences · 1998 · 3.9K citations

Life Sciences, Neurobiology, Neuroscience +15

Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems

Christelle Peyron, Devin K. Tighe, Anthony N. van den Pol et al. · Journal of Neuroscience · 1998 · 3.5K citations · Full text

Medicine, Neurobiology, Neuroscience +14