Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan, +4

Nature Immunology

Lymphocyte DevelopmentImmune Cell DevelopmentAdaptive Immune SystemImmunologyT Cell Immunity +8

IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines

Sophie Molet, Qutayba Hamid, Francis Davoineb, +6

Journal of Allergy and Clinical Immunology

Interleukin-17 promotes angiogenesis and tumor growth

M. Numasaki

Blood

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

Dror Luger, Phyllis B. Silver, Jun Tang, +7

The Journal of Experimental Medicine

Interleukin-17 and Interferon-γ Synergize in the Enhancement of Proinflammatory Cytokine Production by Human Keratinocytes

Marcel B. M. Teunissen, Jan D. Bos, Cock W. Koomen, +2

Journal of Investigative Dermatology

InflammationProinflammatory Cytokine ProductionCytokineInterferon-γ SynergizeImmunology +9

IL-17 Enhances the Net Angiogenic Activity and In Vivo Growth of Human Non-Small Cell Lung Cancer in SCID Mice through Promoting CXCR-2-Dependent Angiogenesis

Muneo Numasaki, Mika Watanabe, Takashi Suzuki, +8

The Journal of Immunology

Inflammatory Molecules in the Tears of Patients with Keratoconus

Isabel Lema, José Antonio Durán

Ophthalmology

InflammationInflammatory MoleculesWound HealingDermatologyMedicine +1

Cutting Edge: IL-17F, a Novel Cytokine Selectively Expressed in Activated T Cells and Monocytes, Regulates Angiogenesis and Endothelial Cell Cytokine Production

Trevor Starnes, Michael J. Robertson, George W. Sledge, +4

The Journal of Immunology

IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis

Martine Chabaud, Erik Lubberts, Leo Joosten, +2

Arthritis Research & Therapy

InflammationRheumatologyCytokineCartilage DegradationMusculoskeletal Research +13

Evidence for a Role of IL-17 in Organ Allograft Rejection: IL-17 Promotes the Functional Differentiation of Dendritic Cell Progenitors

Mary A. Antonysamy, William C. Fanslow, Fumin Fu, +4

The Journal of Immunology

Dendritic CellImmunologyImmune DysregulationInflammationGraft Survival +15