PEGylation of Neuromedin U yields a promising candidate for the treatment of obesity and diabetes

Solid-phase synthesis of protected peptide fragments using a trialkoxy-diphenyl-methylester resin.

H Rink · Tetrahedron Letters · 1987 · 855 citations

Peptide Engineering, Peptide Synthesis, Protected Peptide Fragments +2

A new glucagon and GLP-1 co-agonist eliminates obesity in rodents

Jonathan W. Day, Nickki Ottaway, James T Patterson et al. · Nature Chemical Biology · 2009 · 617 citations · Full text

Obesity, Metabolic Syndrome, Energy Homeostasis +12

Rational Design of a Potent, Long-Lasting Form of Interferon:  A 40 kDa Branched Polyethylene Glycol-Conjugated Interferon α-2a for the Treatment of Hepatitis C

Pascal Bailon, Alicia V. Palleroni, Carol Ann Schaffer et al. · Bioconjugate Chemistry · 2001 · 609 citations

Interferon Alpha-2a, Translational Medicine, Ethylene Glycol +15

Contribution of Linker Stability to the Activities of Anticancer Immunoconjugates

Stephen C. Alley, Dennis R. Benjamin, Scott C. Jeffrey et al. · Bioconjugate Chemistry · 2008 · 456 citations

Immunology, Immunotherapy, Tumor Biology +18

Identification of receptors for neuromedin U and its role in feeding

Andrew D. Howard, Ruiping Wang, Sheng‐Shung Pong et al. · Nature · 2000 · 405 citations

Neuropeptides, Neuroanatomy, Medicine +13