Concepedia

Identification and characterization of stressed degradation products of prulifloxacin using LC–ESI-MS/Q-TOF, MSn experiments: Development of a validated specific stability-indicating LC–MS method

B. China Raju, Manikandan Ramesh, R. Srinivas, S. Satyanarayana Raju, Y. Venkateswarlu

Journal of Pharmaceutical and Biomedical Analysis · 2011 · 37 citations · 15 references

Concepts

BiochemistryDegradation ReactionAnalytical ChemistryMsn ExperimentsLiquid ChromatographyChromatographic AnalysisMedicineStressed Degradation ProductsChromatographyDrug Analysis

References

15

The importance and the challenges of impurity profiling in modern pharmaceutical analysis

Sándor Gǒrög · TrAC Trends in Analytical Chemistry · 2006 · 127 citations

Biochemistry, Modern Pharmaceutical Analysis, Drug Resistance +14

Paraoxonase has a major role in the hydrolysis of prulifloxacin (NM441), a prodrug of a new antibacterial agent.

Katsuhiko Tougou, Akinori Nakamura, Sayaka Watanabe et al. · PubMed · 1998 · 99 citations

Antimicrobial Chemotherapy, Chemical Biology, Enzymatic Modification +18

Susan J. Keam, Caroline M. Perry · Drugs · 2004 · 67 citations

Liquid chromatography/mass spectrometric studies on atorvastatin and its stress degradation products

Ravi P. Shah, Vijay Kumar, Saranjit Singh · Rapid Communications in Mass Spectrometry · 2008 · 55 citations

Drug Degradation Products, Drug Hydrolysis, Biochemistry +15

Capillary electrophoresis–chemiluminescence determination of norfloxacin and prulifloxacin

Zhongju Yang, Xiaoli Wang, Weidong Qin et al. · Analytica Chimica Acta · 2008 · 50 citations

Capillary Electrophoresis, Biochemistry, Bioanalysis +5