Fluorescent sensors for rapid monitoring of intracellular cGMP

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

Eiki Takimoto, Hunter C. Champion, Manxiang Li et al. · Nature Medicine · 2005 · 894 citations

Cardiac Muscle, Cardiomyopathy, Molecular Physiology +9

Novel Single Chain cAMP Sensors for Receptor-induced Signal Propagation

Viacheslav O. Nikolaev, Moritz Bünemann, Lutz Hein et al. · Journal of Biological Chemistry · 2004 · 682 citations · Full text

Engineering, Green Fluorescent Protein, Optogenetics +20

The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding

Sergio E. Martinez, Albert Y. Wu, Natalie A. Glavas et al. · Proceedings of the National Academy of Sciences · 2002 · 285 citations · Full text

Gaf Domains, Phosphodiesterase 2A, Protein Function +15

Spatiotemporal dynamics of guanosine 3′,5′-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator

Akira Honda, Stephen Adams, Carolyn L. Sawyer et al. · Proceedings of the National Academy of Sciences · 2001 · 264 citations · Full text

Interplay of Ca2+ and cAMP Signaling in the Insulin-secreting MIN6 β-Cell Line

L Landa, Mark C. Harbeck, Kelly A. Kaihara et al. · Journal of Biological Chemistry · 2005 · 202 citations · Full text