HPV31 E7 facilitates replication by activating E2F2 transcription through its interaction with HDACs

Human papillomavirus is a necessary cause of invasive cervical cancer worldwide

Jan M.M. Walboomers, Marcel V. Jacobs, M. Michele Manos et al. · The Journal of Pathology · 1999 · 9K citations

The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product

Nicholas J. Dyson, Peter M. Howley, Karl Münger et al. · Science · 1989 · 3K citations

Rb1 Gene Product, Tumor Biology, Retinoblastoma Gene +13

Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence

Masashi Narita, Sabrina Nuñez, Édith Heard et al. · Cell · 2003 · 2.2K citations · Full text

Chromatin, Transcriptional Regulation, Developmental Biology +12

The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

Karl Münger, William C. Phelps, Vivien J. Bubb et al. · Journal of Virology · 1989 · 1.3K citations · Full text

Terminal Differentiation, E7 Genes, Primary Human Keratinocytes +13

E2F integrates cell cycle progression with DNA repair, replication, and G ₂ /M checkpoints

Bing Ren, Hieu Cam, Yasuhiko Takahashi et al. · Genes & Development · 2002 · 1.1K citations · Full text