Pharmacological profiling of native group II metabotropic glutamate receptors in primary cortical neuronal cultures using a FLIPR

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

Sandeep T. Patil, Lu Zhang, Ferenc Martényi et al. · Nature Medicine · 2007 · 1K citations

Psychiatry, Psychotic Disorder, Medicine +12

Reversal of Phencyclidine Effects by a Group II Metabotropic Glutamate Receptor Agonist in Rats

Bita Moghaddam, Barbara W. Adams · Science · 1998 · 1K citations

Psychopharmacology, Pharmacotherapy, Experimental Pharmacology +19

The metabotropic glutamate receptors, MGLUR2 and MGLUR3, show unique postsynaptic, presynaptic and glial localizations

Ronald S. Petralia, Y.-X. Wang, A.S. Niedzielski et al. · Neuroscience · 1996 · 582 citations

Synaptic Plasticity, Metabotropic Glutamate Receptors, Health Sciences +11

Serum‐free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus

Gregory J. Brewer · Journal of Neuroscience Research · 1995 · 542 citations

Effects of ketamine and n-methyl-d-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268

Daniel S. Lorrain, Christopher Baccei, Linda J. Bristow et al. · Neuroscience · 2003 · 429 citations

Psychiatry, Neurophysiology, Neurotransmitter +9