Tissue Antigens · 1974 · 80 citations · 8 references
HistocompatibilityImmunohematologyImmunodeficienciesGeneticsGenetic EpidemiologyImmunologyMolecular BiologyLinkage AnalysisMolecular GeneticsMolecular ResearchGenetic MedicineClinical GeneticsMaximum Likelihood EstimateBiochemical GeneticsPublic HealthMolecular DiagnosticsQuantitative GeneticsHuman Leukocyte AntigenCross-linkStatistical GeneticsChido Negative SubjectsStructural BiologyLinkage DisequilibriumMolecular Diagnostic TechniquesHla TypingMedicine
Of 156 families who were HL‐A typed and Chido‐typed, 15 were found to be suitable for linkage analysis. It was calculated that the odds in favour of linkage of Chido and HL‐A are 1,450,000:1. The maximum likelihood estimate of the Chido : 1.HL‐A recombination fraction is 2½% with 95% confidence limits, obtained graphically, of 0 and 12%; the estimate of the Chido : 2.HL‐A recombination fraction is 1½%, with limits of 0 and 9%. Among Chido negative subjects, the antigens HL‐A12 and W5 occurred more frequently than in a control population.
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The Recombination Fraction of the HL‐A System
Arne Svejgaard, A. Bratlie, P. J. HEDIN et al. · Tissue Antigens · 1971 · 61 citations
Janice Middleton, Marie C. Crookston · Vox Sanguinis · 1972 · 56 citations
A Nebulous Antibody Responsible for Cross‐Matching Difficulties (Chido)
Jean P. Harris, J. Tegoli, Jane L. Swanson et al. · Vox Sanguinis · 1967 · 42 citations