Optics Express · 2009 · 131 citations · 37 references
EngineeringMicroscopyNear FieldBiomedical EngineeringMicro-optical ComponentPlasmonic StructuresPlasmonic TrappingMicrofluidicsBiophysicsNanophotonicsPlasmonic MaterialNanofluidicsPolystyrene SpheresPlasmonicsMicrofabricationBiomedical DiagnosticsApplied PhysicsLab-on-a-chipOptical TrappingNanofabricationMedicine
Near field generated by plasmonic structures has recently been proposed to trap small objects. We report the first integration of plasmonic trapping with microfluidics for lab-on-a-chip applications. A three-layer plasmo-microfluidic chip is used to demonstrate the trapping of polystyrene spheres and yeast cells. This technique enables cell immobilization without the complex optics required for conventional optical tweezers. The benefits of such devices are optical simplicity, low power consumption and compactness; they have great potential for implementing novel functionalities for advanced manipulations and analytics in lab-on-a-chip applications.
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Optical Constants of the Noble Metals
P. B. Johnson, R. W. Christy · Physical review. B, Solid state · 1972 · 19.5K citations
Acceleration and Trapping of Particles by Radiation Pressure
A. Ashkin · Physical Review Letters · 1970 · 4.9K citations · Full text
Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography
Marc Unger, Hou-Pu Chou, Todd Thorsen et al. · Science · 2000 · 4K citations
Microfluidic Large-Scale Integration
Todd Thorsen, Sebastian J. Maerkl, Stephen R. Quake · Science · 2002 · 2.2K citations · Full text
Engineering, Analytical Microsystems, Computer Architecture +16
Optical Trapping and Manipulation of Viruses and Bacteria
A. Ashkin, J. M. Dziedzic · Science · 1987 · 2.1K citations
Photonics, Engineering, Microscopy +12