Polyreactive igm antibodies in the circulation are masked by antigen binding

Naturally occurring antibodies against nine common antigens in human sera. I. Detection, isolation and characterization.

B Guilbert, Guillaume Dighiero, S Avraméas · The Journal of Immunology · 1982 · 664 citations · Full text

Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens.

Elizabeth E. Eynon, David C. Parker · The Journal of Experimental Medicine · 1992 · 428 citations · Full text

Adaptive Immune System, Humoral Response, Immunology +21

Murine hybridomas secreting natural monoclonal antibodies reacting with self antigens.

Guillaume Dighiero, Peggy Lymberi, J C Mazié et al. · The Journal of Immunology · 1983 · 303 citations · Full text

Histocompatibility, Immunohematology, Immunology +20

Monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by CD5+ B cells from patients with rheumatoid arthritis.

Samuele E. Burastero, Paolo Casali, R L Wilder et al. · The Journal of Experimental Medicine · 1988 · 254 citations · Full text

Healthy Subjects, Immunology, Immunotherapy +16

Nucleotide sequences of eight human natural autoantibody VH regions reveals apparent restricted use of VH families.

I Sanz, Paolo Casali, James W. Thomas et al. · The Journal of Immunology · 1989 · 232 citations · Full text

Histocompatibility, Full Length Cdna, Genetics +22