The Mammalian Target of Rapamycin (mTOR) Partner, Raptor, Binds the mTOR Substrates p70 S6 Kinase and 4E-BP1 through Their TOR Signaling (TOS) Motif

mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

Do‐Hyung Kim, Dos D. Sarbassov, Siraj M. Ali et al. · Cell · 2002 · 3K citations · Full text

Nutrient-sensitive Complex, Cell Growth Machinery, Signal Transduction +12

Two TOR Complexes, Only One of which Is Rapamycin Sensitive, Have Distinct Roles in Cell Growth Control

Robbie Loewith, Estela Jacinto, Stephan Wullschleger et al. · Molecular Cell · 2002 · 1.9K citations · Full text

Signal Transduction, Cell Growth Control, Tor Complexes +11

Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action

Kenta Hara, Yoshiko Maruki, K. Yoshino et al. · Cell · 2002 · 1.8K citations · Full text

Protein Secretion, Binding Partner, Signal Transduction +6

Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway

Brendan D. Manning, Andrew R. Tee, M. Nicole Logsdon et al. · Molecular Cell · 2002 · 1.5K citations · Full text

Signal Transduction, Signaling Pathway, Pathology +9

Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism

Kenta Hara, Kazuyoshi Yonezawa, Qing-Ping Weng et al. · Journal of Biological Chemistry · 1998 · 1.4K citations · Full text