Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants

Ethical guidelines for investigations of experimental pain in conscious animals

M. Zimmermann · Pain · 1983 · 7.8K citations

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Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors:  Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1<i>H</i>-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)

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Pharmacy, Medicinal Chemistry, Pharmacology +17

Diversity of group types, regulation, and function of phospholipase A2.

Edward A. Dennis · Journal of Biological Chemistry · 1994 · 1.4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

The pivotal role of tumour necrosis factor α in the development of inflammatory hyperalgesia

Fernando Q. Cunha, Stephen Poole, B. B. Lorenzetti et al. · British Journal of Pharmacology · 1992 · 798 citations · Full text

Veterinary Medicine, Immunology, Pharmacology +16

Interleukin-1β as a potent hyperalgesic agent antagonized by a tripeptide analogue

S. H. Ferreira, B. B. Lorenzetti, Adrian F. Bristow et al. · Nature · 1988 · 624 citations

Life Sciences, Immunology, Pharmacology +14