Concepedia

Oridonin suppresses transplant rejection by depleting T cells from the periphery

Wenzhi Guo, Peiguo Zheng, Jiakai Zhang, Ming Liang, Chuang Zhou, Shuijun Zhang

International Immunopharmacology · 2013 · 19 citations · 16 references

DOI

Concepts

References

16

Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

Yongsheng Li, Li X, Xin Xiao Zheng et al. · Nature Medicine · 1999 · 750 citations

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Apoptosis within spontaneously accepted mouse liver allografts: evidence for deletion of cytotoxic T cells and implications for tolerance induction

Shiguang Qian, Liwei Lu, F Fu et al. · The Journal of Immunology · 1997 · 304 citations · Full text

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CD3-specific antibody–induced immune tolerance involves transforming growth factor-β from phagocytes digesting apoptotic T cells

Sylvain Perruche, Pin Zhang, Yongzhong Liu et al. · Nature Medicine · 2008 · 236 citations

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Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo

Guang‐Biao Zhou, Hui Kang, Lan Wang et al. · Blood · 2006 · 197 citations · Full text

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Localization of Mesenchymal Stromal Cells Dictates Their Immune or Proinflammatory Effects in Kidney Transplantation

Federica Casiraghi, Nadia Azzollini, Marta Todeschini et al. · American Journal of Transplantation · 2012 · 176 citations · Full text

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