Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1β-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.

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Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation.

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Pharmacological analysis of cyclooxygenase-1 in inflammation

Chris Smith, Yan Zhang, Carol M. Koboldt et al. · Proceedings of the National Academy of Sciences · 1998 · 811 citations

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Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-jun N-terminal kinase, and nuclear factor κB: Differential regulation of collagenase 1 and collagenase 3

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Life Sciences, Cell Biology, Immunology +17

Chondrocyte apoptosis induced by nitric oxide.

Francisco J. Blanco, Robert Ochs, Herbert Schwarz et al. · PubMed · 1995 · 629 citations

Life Sciences, Cell Biology, Pathology +8