Gymnema sylvestre R. Br. suspension cell extract show antidiabetic potential in Alloxan induced diabetic albino male rats

Abstract

Abstract Objective To study the antidiabetic effects of suspension cell extract of Gymnema sylvestre (G. sylvestre) along with field grown and wild plants. Methods The effect of ethanolic extracts of the in vitro grown suspension cells of G. sylvestre along with field grown and wild plant leaves of G. sylvestre was tested on alloxan induced diabetic rats. Results While oral administration of the extracts reduced the glucose content in blood and urine, sugar and lipids in serum significantly (P≤0.05), it also increased the body weight, total haemoglobin and plasma protein content. Conclusions It can be concluded that G. sylvestre suspension cell extract show excellent antidiabetic potential against alloxan induced diabetic albino male rats therefore be considered as potent antidiabetic drug.