Concepedia

Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis

J Liu, Heidi L. Weiss, Piotr Rychahou, Lindsey N. Jackson, B. Mark Evers, Tianyan Gao

Oncogene · 2008 · 155 citations · 17 references

DOIFull text

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References

17

High Frequency of Mutations of the <i>PIK3CA</i> Gene in Human Cancers

Yardena Samuels, Zhenghe Wang, Alberto Bardelli et al. · Science · 2004 · 3.4K citations

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

Sheila A. Stewart, Derek M. Dykxhoorn, Deborah Palliser et al. · RNA · 2003 · 1.6K citations · Full text

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Mutant PIK3CA promotes cell growth and invasion of human cancer cells

Yardena Samuels, Luis A. Díaz, Oleg Schmidt‐Kittler et al. · Cancer Cell · 2005 · 919 citations · Full text

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PHLPP: A Phosphatase that Directly Dephosphorylates Akt, Promotes Apoptosis, and Suppresses Tumor Growth

Tianyan Gao, Frank B. Furnari, Alexandra C. Newton · Molecular Cell · 2005 · 911 citations · Full text

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Multiple Roles of the PI3K/PKB (Akt) Pathway in Cell Cycle Progression

Jiyong Liang, Joyce M. Slingerland · Cell Cycle · 2003 · 884 citations

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