Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1,4-di-N-oxide

The invention of new radical chain reactions. Part VIII. Radical chemistry of thiohydroxamic esters; A new method for the generation of carbon radicals from carboxylic acids

Derek H. R. Barton, David Crich, William B. Motherwell · Tetrahedron · 1985 · 528 citations

Natural Sciences, Chemistry, Organic Chemistry +11

Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses

Robert Hertzberg, Peter B. Dervan · Biochemistry · 1984 · 468 citations

Pharmacy, Biochemistry, Molecular Biology +13

Carbon—Hydrogen Bonds of DNA Sugar Units as Targets for Chemical Nucleases and Drugs

Geneviève Pratviel, Jean Bernadou, Bernard Meunier · Angewandte Chemie International Edition in English · 1995 · 420 citations

Life Sciences, Biochemistry, Molecular Biology +17

A comparison of the specificities of xanthine oxidase and aldehyde oxidase

Thomas A. Krenitsky, Shannon M. Neil, Gertrude B. Elion et al. · Archives of Biochemistry and Biophysics · 1972 · 342 citations

Life Sciences, Biochemistry, Biocatalysis +3

Molecular mechanisms for the hypoxiadependent activation of 3-amino-1,2,4-benzotriazine-1, 4-dioxide (SR 4233)

Keith R. Laderoute, Peter Wardman, Andrew M. Rauth · Biochemical Pharmacology · 1988 · 156 citations

Life Sciences, Biochemistry, Pharmacology +12