Targeting bcl-2 gene to delay androgen-independent progression and enhance chemosensitivity in prostate cancer using antisense bcl-2 oligodeoxynucleotides

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

Yuri Lazebnik, Scott H. Kaufmann, Serge Desnoyers et al. · Nature · 1994 · 2.6K citations

Life Sciences, Biochemistry, Molecular Biology +10

Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma.

Y Tsujimoto, Carlo M. Croce · Proceedings of the National Academy of Sciences · 1986 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer.

Timothy J. McDonnell, Patricia Troncoso, Shawn Brisbay et al. · PubMed · 1992 · 1.1K citations

Medicine, Oncology, Urology +17

Taxol induces bcl-2 phosphorylation and death of prostate cancer cells.

Subrata Haldar, Janaki Chintapalli, C M Croce · PubMed · 1996 · 662 citations

Medicine, Oncology, Pharmacology +13

Bcl2 is the guardian of microtubule integrity.

Swati Haldar, Aruna Basu, Carlo M. Croce · PubMed · 1997 · 599 citations

Medicine, Oncology, Pharmacology +17