Berberine decreases PCSK9 expression in HepG2 cells

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

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Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

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Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

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Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

Weijia Kong, Jing Wei, Parveen Abidi et al. · Nature Medicine · 2004 · 1.4K citations

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Binding of Proprotein Convertase Subtilisin/Kexin Type 9 to Epidermal Growth Factor-like Repeat A of Low Density Lipoprotein Receptor Decreases Receptor Recycling and Increases Degradation

Dawei Zhang, Thomas A. Lagace, Rita Garuti et al. · Journal of Biological Chemistry · 2007 · 784 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17