The NF-κB inhibitor diethyldithiocarbamate (DDTC) increases brain cell death in a transient middle cerebral artery occlusion model of ischemia

Reversible middle cerebral artery occlusion without craniectomy in rats.

Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke · 1989 · 7.4K citations · Full text

Mca Occlusion, Cerebral Vascular Regulation, Neurovascular Disease +18

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

Amer A. Beg, David Baltimore · Science · 1996 · 3.1K citations

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

Yuri Lazebnik, Scott H. Kaufmann, Serge Desnoyers et al. · Nature · 1994 · 2.6K citations

Protein Chemistry, Biochemistry, Viral Polymerase Structure +6

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

Ralf Schreck, Beate Meier, Daniela N. Männel et al. · The Journal of Experimental Medicine · 1992 · 1.5K citations · Full text

Intact Cells, Antioxidant Pdtc, Immunology +21

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

Markus Meyer, Ralf Schreck, Patrick A. Baeuerle · The EMBO Journal · 1993 · 1.3K citations · Full text

Inflammation, Redox Signaling, Intact Cells +12