Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

S. E. Luria, M. Delbrück · Genetics · 1943 · 3.9K citations

Life Sciences, Genetics, Microbiology +17

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Yurij Ionov, Miguel A. Peinado, Sergei Malkhosyan et al. · Nature · 1993 · 2.7K citations

Medicine, Genetics, Molecular Genetics +17

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

Jef D. Boeke, Francois La Croute, Gerald R. Fink · Molecular and General Genetics MGG · 1984 · 2.4K citations

Life Sciences, Genetics, Molecular Biology +8

The distribution of the numbers of mutants in bacterial populations

D. E. Lea, C. A. Coulson · Journal of Genetics · 1949 · 1.5K citations

Life Sciences, Biology, Microbiology +11

Frameshift Mutations and the Genetic Code

George Streisinger, Yasushi Okada, Joyce Emrich et al. · Cold Spring Harbor Symposia on Quantitative Biology · 1966 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +10