Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice

Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

Michaël Weber, Ines Hellmann, Michael Stadler et al. · Nature Genetics · 2007 · 2.3K citations

Medicine, Genetics, Molecular Genetics +16

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

Laura R. Livingstone, Alicia White, Jason Sprouse et al. · Cell · 1992 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +16

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

Jason I. Herschkowitz, Karl Simin, Victor Weigman et al. · Genome biology · 2007 · 1.3K citations · Full text

Life Sciences, Genetics, Oncology +17

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

William J. Muller, Eric Sinn, Paul K. Pattengale et al. · Cell · 1988 · 1.2K citations

Medicine, Cancer Biology, Oncology +14

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles

Yuxin Yin, Michael A. Tainsky, Farideh Z. Bischoff et al. · Cell · 1992 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +17