D-chiro-inositol glycan stimulates insulin secretion in pancreatic β cells

Intracellular ATP directly blocks K+ channels in pancreatic B-cells

Daniel L. Cook, Nicholas M. Hales · Nature · 1984 · 1.2K citations

Signal Transduction, Molecular Physiology, Physiology +6

Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes

Rohit Kulkarni, Jens C. Brüning, Jonathon N. Winnay et al. · Cell · 1999 · 1.1K citations · Full text

Insulin Resistance, Insulin Signaling, Molecular Physiology +13

Insulin Stimulates Testosterone Biosynthesis by Human Thecal Cells from Women with Polycystic Ovary Syndrome by Activating Its Own Receptor and Using Inositolglycan Mediators as the Signal Transduction System¹

John E. Nestler, Daniela Jakubowicz, Aı́da Falcón de Vargas et al. · The Journal of Clinical Endocrinology & Metabolism · 1998 · 572 citations

Immunology, Gynecology, Polycystic Ovary Syndrome +25

Insulin Stimulates Testosterone Biosynthesis by Human Thecal Cells from Women with Polycystic Ovary Syndrome by Activating Its Own Receptor and Using Inositolglycan Mediators as the Signal Transduction System

John E. Nestler · The Journal of Clinical Endocrinology & Metabolism · 1998 · 431 citations

Infertility, Signal Transduction, Endocrine Mechanism +15

Identification of a vesicular nucleotide transporter

Keisuke Sawada, Noriko Echigo, Narinobu Juge et al. · Proceedings of the National Academy of Sciences · 2008 · 411 citations · Full text

Slc17a9 Protein, Protein Secretion, Synaptic Transmission +21