A role for Bach1 and HO-2 in suppression of basal and UVA-induced HO-1 expression in human keratinocytes

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

Petra Boukamp, R T Petrussevska, Dirk Breitkreutz et al. · The Journal of Cell Biology · 1988 · 4.1K citations · Full text

Skin Development, Cell Division, Cutaneous Biology +11

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh et al. · Genes & Development · 1999 · 3.5K citations · Full text

Lipid Peroxidation, Molecular Biology, Redox Biology +18

Reduced stress defense in heme oxygenase 1-deficient cells

Kenneth D. Poss, Susumu Tonegawa · Proceedings of the National Academy of Sciences · 1997 · 1.3K citations · Full text

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.

Stephen M. Keyse, Rex M. Tyrrell · Proceedings of the National Academy of Sciences · 1989 · 1.3K citations · Full text

Biochemistry, Heme Homeostasis, Natural Sciences +15

Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency

Akihiro Yachie, Yo Niida, Taizo Wada et al. · Journal of Clinical Investigation · 1999 · 1.3K citations · Full text