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Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 1: Discovery of novel orally active inhibitors of human thymidine phosphorylase

Medicinal ChemistryDerivative (Chemistry)BiochemistryNatural SciencesActive InhibitorsHuman Thymidine PhosphorylaseMedicineDrug DevelopmentChemical BiologyPharmacologyPharmaceutical ChemistrySynthetic ChemistryDrug Discovery6-Methylene-bridged Uracil Derivatives