Concepedia

Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses

Cláudia G. Almeida, Davide Tampellini, Reisuke H. Takahashi, Paul Greengard, Michael T. Lin, Eric M. Snyder, Gunnar K. Gouras

Neurobiology of Disease · 2005 · 389 citations · 37 references

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37

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

Robert D. Terry, Eliezer Masliah, David P. Salmon et al. · Annals of Neurology · 1991 · 4.4K citations

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Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Dominic M. Walsh, Igor Klyubin, Julia V. Fadeeva et al. · Nature · 2002 · 4.3K citations

, , +14

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron · 2003 · 4.1K citations · Full text

, , +12

High-Level Neuronal Expression of Aβ<sub>1–42</sub>in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu et al. · Journal of Neuroscience · 2000 · 1.9K citations · Full text

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Soluble pool of A? amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

Catriona McLean, Robert A. Cherny, Fiona Fraser et al. · Annals of Neurology · 1999 · 1.8K citations

, , +17