Combination of chemokine and angiogenic factor genes and mesenchymal stem cells could enhance angiogenesis and improve cardiac function after acute myocardial infarction in rats

Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts

Abeel A. Mangi, Nicolas Noiseux, Deling Kong et al. · Nature Medicine · 2003 · 1.5K citations

Engineering, Biotechnology, Cardiology +9

Marrow-Derived Stromal Cells Express Genes Encoding a Broad Spectrum of Arteriogenic Cytokines and Promote In Vitro and In Vivo Arteriogenesis Through Paracrine Mechanisms

Timothy Kinnaird, Eugenio Stabile, Mary Susan Burnett et al. · Circulation Research · 2004 · 1.4K citations · Full text

Engineering, Bioengineering, Cell Biology +17

Evidence supporting paracrine hypothesis for Akt‐modified mesenchymal stem cell‐mediated cardiac protection and functional improvement

Massimiliano Gnecchi, Huamei He, Nicolas Noiseux et al. · The FASEB Journal · 2006 · 1.1K citations

Life Sciences, Cardiology, Physiology +17

VEGF-Induced Adult Neovascularization: Recruitment, Retention, and Role of Accessory Cells

Myriam Grunewald, Inbal Avraham, Yuval Dor et al. · Cell · 2006 · 1.1K citations · Full text

Life Sciences, Bioengineering, Cell Biology +14

Stromal Cell–Derived Factor-1α Plays a Critical Role in Stem Cell Recruitment to the Heart After Myocardial Infarction but Is Not Sufficient to Induce Homing in the Absence of Injury

J. Dawn Abbott, Yan Huang, Dingang Liu et al. · Circulation · 2004 · 789 citations · Full text

Medicine, Cardiology, Cell Biology +5