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Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

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Engineering, Dna Analysis, Molecular Biology +19

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

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Biosynthesis, Nucleic Acid Chemistry, Biochemistry +6

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

RK Saiki, DH Gelfand, Susanne Stoffel et al. · Science · 1988 · 4.3K citations

Thermostable Dna Polymerase, Polymerase Chain Reaction, Nucleic Acid Chemistry +9

Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability

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Lynch Syndrome, Cancer Pathology, Medicine +14

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Yurij Ionov, Miguel A. Peinado, Sergei Malkhosyan et al. · Nature · 1993 · 2.7K citations

Somatic Variant, Tumor Heterogeneity, Ubiquitous Somatic Mutations +6