A Mild and Efficient Method for <i>N</i>‐Arylnucleobase Synthesis <i>via</i> the Cross‐Coupling Reactions of Nucleobases with Arylboronic Acids Catalyzed by Simple Copper Salts

Abstract

Abstract A simple and efficient copper‐salt catalyzed N ‐arylation of nucleobases is reported. In a mixed solvent of MeOH and H 2 O, the coupling products were obtained in moderate to excellent yields at room temperature within a short time. A variety of substituted N ‐aryl nucleobases can be prepared through this procedure.