Production of human insulin in anE. coli system with Met-Lys-human proinsulin as the expressed precursor

Molecular cloning: A laboratory manual

Prescott L. Deininger · Analytical Biochemistry · 1990 · 86.2K citations

Life Sciences, Molecular Biology, Molecular Genetics +11

Cold Spring Harbor Laboratory; Cold Spring Harbor, NY

T. Cavalier-Smith · FEBS Letters · 1980 · 6.3K citations · Full text

Life Sciences, Microbiology, Microbial Genomics +1

Expression in Escherichia coli of chemically synthesized genes for human insulin.

David V. Goeddel, Dennis G. Kleid, Francisco Bolívar et al. · Proceedings of the National Academy of Sciences · 1979 · 864 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Studies on the Conversion of Proinsulin to Insulin

Wolfgang Kemmler, James D. Peterson, Donald F. Steiner · Journal of Biological Chemistry · 1971 · 214 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Bacteria mature preproinsulin to proinsulin.

Karen Talmadge, Jim Kaufman, W Gilbert · Proceedings of the National Academy of Sciences · 1980 · 142 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17