Concepedia

Hormone Precursor Processing

Hormone Precursor Processing is a biochemical mechanism within the broader category of proteolytic processing that specifically involves the enzymatic cleavage of inactive prohormone molecules to generate biologically active peptide hormones.

686

Publications

38.5K

Citations

2K

Authors

526

Institutions

Publications per year

2017–2026

9

Parents

Publications

686

Common precursor to corticotropins and endorphins

Richard E. Mains, Betty Eipper, Nicholas Ling · Proceedings of the National Academy of Sciences · 1977 · 1.1K citations · Full text

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Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway

Masahiro Hosaka, Masami Nagahama, W.S. Kim et al. · Journal of Biological Chemistry · 1991 · 598 citations · Full text

, , +17

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans.

Steven P. Smeekens, Anthony Avruch, J LaMendola et al. · Proceedings of the National Academy of Sciences · 1991 · 451 citations

, , +16

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2

Machi Furuta, Hideki Yano, An Zhou et al. · Proceedings of the National Academy of Sciences · 1997 · 428 citations

, , +17

Thyrotropin-Releasing Hormone Precursor: Characterization in Rat Brain

Ronald M. Lechan, Ping Wu, Ivor M.D. Jackson et al. · Science · 1986 · 354 citations

, , +15

1–5 of 686

Authors

2K

  1. NG
    Nabil G. Seidah

    Montreal Clinical Research Institute, Canada

    32 publications · 1.9K citations

    25

    h-index

  2. DF
    Donald F. Steiner

    University of Chicago, United States

    25 publications · 3K citations

    21

    h-index

  3. RE
    Richard E. Mains

    Johns Hopkins University, United States

    22 publications · 2.6K citations

    18

    h-index

  4. IL
    Iris Lindberg

    University Medical Center New Orleans, United States

    20 publications · 939 citations

    16

    h-index

  5. MC
    Michel Chrétien

    Montreal Clinical Research Institute, Canada

    19 publications · 1.1K citations

    16

    h-index

1–5 of 2K

Institutions

526

  1. Rhode Island Hospital

    Providence, United States

    24 h-index

    73 publications

    5K citations

  2. Montreal Clinical Research Institute

    Montreal, Canada

    22 h-index

    101 publications

    5.6K citations

  3. University of Chicago

    Chicago, United States

    21 h-index

    90 publications

    12.4K citations

  4. Albert Einstein College of Medicine

    Bronx, United States

    20 h-index

    65 publications

    4.2K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    20 h-index

    88 publications

    14.7K citations

  6. Massachusetts General Hospital

    Boston, United States

    19 h-index

    87 publications

    6K citations

  7. Johns Hopkins University

    Baltimore, United States

    19 h-index

    72 publications

    6.9K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    18 h-index

    75 publications

    3.9K citations

1–8 of 526

Venues

  1. Journal of Biological Chemistry

    JBC · 118 publications · 8.5K citations

    56

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 50 publications · 7.2K citations

    40

    h-index

  3. Endocrinology

    93 publications · 3.6K citations

    38

    h-index

  4. FEBS Letters

    26 publications · 1.2K citations

    20

    h-index

  5. Molecular Endocrinology

    20 publications · 1.2K citations

    18

    h-index

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