Concepedia

A novel targeted delivery system utilizing a cephalosporin-oncolytic prodrug activated by an antibody β-lactamase conjugate for the treatment of cancer

Timothy A. Shepherd, Louis N. Jungheim, Damon L. Meyer, James J. Starling

Bioorganic & Medicinal Chemistry Letters · 1991 · 56 citations · 15 references

DOI

Concepts

References

15

Selective cleavage of the allyl and (allyloxy)carbonyl groups through palladium-catalyzed hydrostannolysis with tributyltin hydride. Application to the selective protection-deprotection of amino acid derivatives and in peptide synthesis

Olivier Dangles, F. GUIBE, G.G.A. Balavoine et al. · The Journal of Organic Chemistry · 1987 · 259 citations

, , +13

Homogeneous, palladium(0)-catalyzed exchange deprotection of allylic esters, carbonates and carbamates

Paul D. Jeffrey, Stuart W. McCombie · The Journal of Organic Chemistry · 1982 · 237 citations

, , +9

Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate.

Mark G. Saulnier, George J. Schreiber, David L. Hirschberg et al. · Proceedings of the National Academy of Sciences · 1988 · 235 citations · Full text

, , +17

Purification of <i>β</i>-lactamases by affinity chromatography on phenylboronic acid-agarose

Steven Cartwright, S G Waley · Biochemical Journal · 1984 · 148 citations · Full text

, , +10

Novel prodrugs which are activated to cytotoxic alkylating agents by carboxypeptidase G2

Caroline J. Springer, Pari Antoniw, Bagshawe et al. · Journal of Medicinal Chemistry · 1990 · 134 citations

, , +17