Prenatal Exposure to Lipopolysaccharide Combined with Pre- and Postnatal High-Fat Diet Result in Lowered Blood Pressure and Insulin Resistance in Offspring Rats

Abstract

Prenatal exposure to lipopolysaccharide combined with pre- and postnatal high-fat diet result in lowered blood pressure, insulin resistance and impaired liver function in three-month old offspring rats. The lowered blood pressure might benefit from the predictive adaptive response to prenatal inflammation.