Differential Inhibition of Cutaneous T-Cell-Mediated Reactions and Epidermal Cell Proliferation by Cyclosporin A, FK-506, and Rapamycin

FK 506 FOR LIVER, KIDNEY, AND PANCREAS TRANSPLANTATION

ThomasE. Starzl, John J. Fung, Raman Venkataramman et al. · The Lancet · 1989 · 1.1K citations

Medicine, Pharmacokinetics, Surgery +12

The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes.

Michael J. Tocci, D A Matkovich, Kathy Collier et al. · The Journal of Immunology · 1989 · 670 citations

Life Sciences, Immunology, Pharmacology +16

Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin.

Francis J. Dumont, Mary Jo Staruch, Sam L. Koprak et al. · The Journal of Immunology · 1990 · 609 citations

Life Sciences, Immunology, Pharmacology +8

Cyclosporine for Plaque-Type Psoriasis

Charles N. Ellis, Mark S. Fradin, Joseph M. Messana et al. · New England Journal of Medicine · 1991 · 432 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +6

Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions.

P F Piguet, Georges E. Grau, Carl J. Hauser et al. · The Journal of Experimental Medicine · 1991 · 342 citations · Full text

Veterinary Medicine, Dermatology, Immunology +17