Concepedia

Publication | Open Access

miR-375 Inhibits Autophagy and Reduces Viability of Hepatocellular Carcinoma Cells Under Hypoxic Conditions

DOIFull Paper Access

286

Citations

49

References

2012

Year

Ying Chang, Wei Yan, Xingxing He, Lemeng Zhang, Chuanjiang Li, Hai Huang, Gary Nace, David A. Geller, Jusheng Lin, Allan Tsung
Gastroenterology

Abstract

miR-375 inhibits autophagy by reducing expression of ATG7 and impairs viability of HCC cells under hypoxic conditions in culture and in mice. miRNAs that inhibit autophagy of cancer cells might be developed as therapeutics.

References

YearCitations

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