Taurine supplementation induces multidrug resistance protein 2 and bile salt export pump expression in rats and prevents endotoxin-induced cholestasis

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

Jeff L. Staudinger, Bryan Goodwin, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 2001 · 1.4K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13

Regulation of Multidrug Resistance-associated Protein 2 (ABCC2) by the Nuclear Receptors Pregnane X Receptor, Farnesoid X-activated Receptor, and Constitutive Androstane Receptor

Heidi R. Kast-Woelbern, Bryan Goodwin, Paul T. Tarr et al. · Journal of Biological Chemistry · 2002 · 908 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

The antioxidant action of taurine, hypotaurine and their metabolic precursors

Okezie I. Aruoma, Barry Halliwell, Brigid M. Hoey et al. · Biochemical Journal · 1988 · 580 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis

Michael Trauner, Marco Arrese, CJ Soroka et al. · Gastroenterology · 1997 · 499 citations

Life Sciences, Biochemistry, Pharmacology +17

Cloning and expression of a high affinity taurine transporter from rat brain.

Kelli E. Smith, Laurence A. Borden, C H Wang et al. · Molecular Pharmacology · 1992 · 268 citations

Life Sciences, Molecular Biology, Neuroscience +13