A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald

Cell

Genome InstabilityNovel GeneGenetic DisorderNatural SciencesGenetics +8

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller, +8

Cell

Knockout MouseNeurodegenerative DiseasesDevelopmental BiologyExon 1Genetic Disorder +7

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase, +4

Science

Huntington's Disease

Jean Stipe, Dorothy A. White, Eleanor Van Arsdale

AJN American Journal of Nursing

Rare DiseasesGenetic DisorderRare CasesAfflicted ParentPediatrics +2

Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside isolated from human teratocarcinoma cells.

Reiji Kannagi, Nancy A. Cochran, Fumitsugu Ishigami, +4

The EMBO Journal

Tumoral PathologyTumor InnervationImmunologyPathologyHuman Teratocarcinoma Cells +6

Widespread expression of Huntington's disease gene (IT15) protein product

Alan H. Sharp, Scott J. Loev, Gabriele Schilling, +12

Neuron

Structure and expression of the Huntington's disease gene: Evidence against simple inactivation due to an expanded CAG repeat

Christine Ambrose, Mabel P. Duyao, Glenn Barnes, +18

Somatic Cell and Molecular Genetics

Genetic DisorderNatural SciencesGeneticsDisease GeneGenomic Mechanism +9

Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans

Ana Knežević, Olga Gornik, Ozren Polašek, +8

Glycobiology

Patterns of cell loss in Huntington's disease

Neil W. Kowall, Robert J. Ferrante, Joseph B. Martin

Trends in Neurosciences

GeneticsCell LossDegenerative DiseaseNeurodegenerationMedicine +1

Mice lacking both subunits of lysosomal β–hexosaminidase display gangliosidosis and mucopolysaccharidosis

Kazunori Sango, Michael P. McDonald, Jacqueline N. Crawley, +8

Nature Genetics

PathogenesisPathologyMedicineCell BiologyLysosomal Storage Disease +1