Concepedia

Microparticles Carrying Sonic Hedgehog Favor Neovascularization through the Activation of Nitric Oxide Pathway in Mice

Tarek Benameur, Raffaella Soleti, Chiara Porro, Ramaroson Andriantsitohaina, Maria Carmen Martínez

PLoS ONE · 2010 · 96 citations · 28 references

DOIFull text

Open access

Abstract

These findings suggest that MPs(Shh+) may contribute to reparative neovascularization after ischemic injury by regulating NO pathway and genes involved in angiogenesis.

References

28

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Jo Vandesompele, Katleen De Preter, Filip Pattyn et al. · Genome biology · 2002 · 19.7K citations · Full text

Mouse model of angiogenesis.

Thierry Couffinhal, David M. Silver, Lu Zheng et al. · PubMed · 1998 · 670 citations

The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors

Roberto Pola, Leona Ling, Marcy Silver et al. · Nature Medicine · 2001 · 604 citations

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Shedding of the Matrix Metalloproteinases MMP-2, MMP-9, and MT1-MMP as Membrane Vesicle-Associated Components by Endothelial Cells

Giulia Taraboletti, Sandra D’Ascenzo, Patrizia Borsotti et al. · American Journal Of Pathology · 2002 · 565 citations · Full text

, , +16

Intracoronary gene transfer of fibroblast growth factor–5 increases blood flow and contractile function in an ischemic region of the heart

Frank J. Giordano, Peipei Ping, M. Dan McKirnan et al. · Nature Medicine · 1996 · 486 citations

, , +12