Concepedia

From Single Cells to Tissues: Interactions between the Matrix and Human Breast Cells in Real Time

Clifford A. Barnes, Lucía Speroni, Kyle P. Quinn, Maël Montévil, Kurt Saetzler, Gbemisola Bode-Animashaun, McKerr George, Irene Georgakoudi, C. Stephen Downes, Carlos Sonnenschein,

PLoS ONE · 2014 · 49 citations · 30 references

DOIFull text

Open access

Abstract

Localized regions of collagen fiber alignment are required for ductal elongation and branching suggesting the importance of local mechanical anisotropy in mammary epithelial morphogenesis. Similar principles may govern the morphology of branching and budding in other tissues and organs.

References

30

A guided tour into subcellular colocalization analysis in light microscopy

Susanne Bolte, Fabrice P. Cordelières · Journal of Microscopy · 2006 · 5.4K citations

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Tensional homeostasis and the malignant phenotype

Matthew J. Paszek, Nastaran Zahir, Kandice R. Johnson et al. · Cancer Cell · 2005 · 3.9K citations

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Collagen reorganization at the tumor-stromal interface facilitates local invasion

Paolo P. Provenzano, Kevin W. Eliceiri, Jay M. Campbell et al. · BMC Medicine · 2006 · 1.8K citations · Full text

Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis

Muhammad H. Zaman, Linda M. Trapani, Alisha L. Sieminski et al. · Proceedings of the National Academy of Sciences · 2006 · 1.2K citations · Full text

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Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

Katarina Wolf, Yi Wu, Yueying Liu et al. · Nature Cell Biology · 2007 · 985 citations · Full text

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