Tumor progression induced by the loss of E-cadherin independent of β-catenin/Tcf-mediated Wnt signaling

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

Vladimír Kořínek, Nick Barker, Patrice J. Morin et al. · Science · 1997 · 3.3K citations

Tcf Reporter Gene, Pathology, Cancer Biology +18

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

Kris Vleminckx, L. Vakaet, M. Mareel et al. · Cell · 1991 · 1.7K citations

Cancer Research, Medicine, Epithelial Tumor Cells +8

A causal role for E-cadherin in the transition from adenoma to carcinoma

Anne‐Karina T. Perl, Petra Wilgenbus, Ulf Dahl et al. · Nature · 1998 · 1.4K citations

Tumor Biology, Malignant Disease, Medicine +10

Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

Douglas Hanahan · Nature · 1985 · 1.3K citations

Pancreatic Cancer, Transgenic Mouse Models, Pancreatic β-Cell Tumours +8

Intestinal polyposis in mice with a dominant stable mutation of the beta -catenin gene

Naomoto Harada · The EMBO Journal · 1999 · 1.2K citations · Full text

Intestinal Polyposis, Genetics, Pathogenesis +7