CB1 receptor selective activation inhibits β-amyloid-induced iNOS protein expression in C6 cells and subsequently blunts tau protein hyperphosphorylation in co-cultured neurons

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

Inge Grundke‐Iqbal, Khalid Iqbal, M Quinlan et al. · Journal of Biological Chemistry · 1986 · 1.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

CB1 Cannabinoid Receptors and On-Demand Defense Against Excitotoxicity

Giovanni Marsicano, Sharon Goodenough, Krisztina Monory et al. · Science · 2003 · 1.2K citations

Medicine, Neuroscience, Pharmacology +17

Prevention of Alzheimer's Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation

Belén G. Ramírez, Cristina Blázquez, Teresa Gómez del Pulgar et al. · Journal of Neuroscience · 2005 · 779 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Cannabinoid CB₂Receptors and Fatty Acid Amide Hydrolase Are Selectively Overexpressed in Neuritic Plaque-Associated Glia in Alzheimer's Disease Brains

Cristina Benito, Estefanía Núñez, Rosa M. Tolón et al. · Journal of Neuroscience · 2003 · 618 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures

Tetsuya Nagayama, Amy D. Sinor, Roger P. Simon et al. · Journal of Neuroscience · 1999 · 469 citations · Full text

Medicine, Neuroscience, Pharmacology +17